The beginning of the timetable is expected to be delayed by around 40 minutes when it starts up on June 1.
A spokesperson for the Tyne and Wear Metro said: “The morning peak services will be cancelled.
"Staff will assess the passenger levels to arrange additional trains to assist where possible.
"We are sorry for the inconvenience this may cause.
"Please check for updates from 5am.”
Passengers are also being warned there will be no trains between Airport and Regents Centre on June 12 and 13 to allow for over head power line work, with the replacement bus service 900 to operate.
Kingston Park level crossing will be closed all day, with a shuttle bus to run from about 5.20am until 12.20am, to take people to the opposite side of the tracks.