The A1068 in Alnwick is closed between the Oaks Hotel and Lesbury after a collision.
Police received a report of the one-car crash at around 2.50pm today.
The circumstances of the collision are still being established and it’s believed one woman is injured and although the extent of injuries are not yet known they are not believed to be life-threatening
The road remains closed for the Great North Air Ambulance to land.
Motorists are advised they may experience delays and police are controlling traffic.