A third accident in nine days has closed the A697 north of Morpeth.
The road is currently closed after a collision near Longhorsley.
This follows fatal collisions in the same area on Saturday morning and last Tuesday afternoon.
A spokeswoman for Northumbria Police said: “Police received a report at 4.11pm of a collision on the A697 two miles south of Longhorsley
“Police and the ambulance service are at the scene now.
“The road has been closed temporarily and diversions are in place.”